Providing independent clinical excellence since 2005
Traditional health improvement plans assume everyone responds the same way. Real life tells us otherwise. N-of-1 explains how to use a personalised, precision-medicine approach to reduce visceral fat, stabilise metabolism and rebuild long-term health. Through weekly reflections, practical tools and small self-experiments, the book guides you to uncover what truly works for you — not for the average patient, but for your own unique physiology.
VAT is the principal metabolic culprit in cardiovascular risk. BMI—while simple—fails to capture fat distribution, muscle mass, or ageing effects. Waist-based anthropometrics, particularly waist circumference and waist-to-height ratio, more closely reflect VAT and strongly predict cardiovascular outcomes.For cardiologists, this explains why a tape measure around the waist is more valuable than a BMI calculation. Where precise measurement is required—such as in high-risk patients commencing GLP-1 therapy—DEXA and low-dose CT provide direct VAT quantification.In both prevention and clinical practice, tracking waist measurements makes far more sense than relying on BMI.
Cardiology groups, including ours, are increasingly partnering with diabetes and weight management specialists to set up GLP-1 mimetic clinics. These clinics oversee VAT loss and improve glycaemic control for patients with diverse cardiac conditions. The goal is not only to help these patients manage their symptoms but also to provide a holistic approach to cardiovascular and metabolic health, with an emphasis on reducing the burden of visceral fat. Specialist clinics offer patients the chance to access personalised care that targets both fat loss and better glucose regulation, reducing the need for medications and potentially improving overall quality of life. In this blog and associated podcast and YouTube explainer, we set out some of the fundamental principles we care about.
Most men over 30 will recognise the slow but steady expansion of the waistline. Whether you call it a spare tyre, a dad bod, or just a bit of extra padding, not all belly fat is created equal — and not all of it is harmless.Some types of abdominal fat are mostly cosmetic. Others are dangerous, inflammatory, and metabolically active — the kind of fat that silently drives heart attacks, strokes, dementia, and even advanced cancers.Let’s break down the three main culprits behind the male belly — and what you can do about them.
GLP-1 therapy is most effective when paired with sustainable lifestyle improvements. That’s why our clinic operates on a shared care agreement—we commit to providing access to these powerful medications, while you commit to making meaningful changes in diet, exercise, sleep, and stress management.
An article written by Dr Edward Leatham, Consultant Cardiologist Tags: Podcast, AFib, Bradycardia, NH1 search website using Tags to find related stories. Introduction Pulse rate or heart rate is a fundamental metric of heart health. It’s easily accessible—whether through feeling the […]
This post is not for the faint hearted! It is a technical description of how the heart works, and may help some readers/listeners to understand the difference between HFpEF and HFrEF. The main objective of this blog is to emphasise the enormous potential of reducing left ventricular stiffening as we age. This can only be accomplished by paying attention to key health metrics from mid life, all influenced by lifestyle, diet and physical exercise
A slow heart rate may not cause symptoms in many people. However, when bradycardia leads to insufficient blood flow, symptoms may arise. The causes of bradycardia are discussed and what constitutes a normal range. An associated podcast is available too.
In atrial fibrillation or AFib, the atrial tissue quivers at approximately 600 cycles per minute, which means that it has no useful pumping function. The left atrium therefore, in patients with atrial fibrillation, merely acts as a passive conduit between the lungs and the left ventricle. It no longer serves to prime the left ventricle, and as a result, less blood enters the heart during diastole, less 'priming' occurs so cardiac output may fall. If ever you have experienced a car's turbo charger going 'on the blink' you will know that the car still GOES, but not very well, since it too suffers loss of output. The left atrial pressure in many such cases will increase, causing oedema or fluid in the alveolar space, reducing gas exchange and contributing to the symptom of breathlessness.
For a cardiologist, beta blockers are a commonly used medication, possibly because we live in a high stress world and patients come to us with symptoms that are often improved by moderating the biological effects of our own adrenaline on the systems it was designed to protect.