Skip to main content

Providing independent clinical excellence since 2005

The SCVC Blog

Cardiovascular care news and articles from our expert team

How a daily junior aspirin can save millions of lives

Aspirin, or acetylsalicylic acid, is one of the oldest and most widely used medications in the world. Well known for its analgesic effects, it was later discovered to be effective in much smaller doses in preventing platelet aggregation that had a pivotal role in arterial thrombosis. Its  role in inhibiting platelet activity has made it a cornerstone in the prevention and treatment of arterial thrombosis. In this article, we will explore the fascinating role of platelets in acute coronary thrombosis, the mechanisms by which aspirin exerts its protective effects, and the clinical considerations for its use.

When to Operate in Aortic Stenosis: Timing, Symptoms, and Considerations for Intervention

The timing of intervention in aortic stenosis is critical. Delaying surgery or transcatheter procedures until symptoms become severe or complications arise can lead to poorer outcomes. Conversely, intervening too early may expose patients to unnecessary procedural risks. For exceptionally fit individuals aged 75-85, timely intervention can be particularly advantageous, as they may tolerate surgical aortic valve replacement (SAVR) better than expected for their age. In these cases, earlier treatment may prevent irreversible damage to the heart and reduce the risks associated with waiting until the disease progresses further.

Aortic Stenosis

Aortic stenosis (AS) is a progressive and potentially life-threatening condition. It predominantly affects older adults and has significant implications for cardiovascular health, life expectancy, and quality of life.  The incidence of AS is climbing because of increased life expectancy. Timely intervention, especially in symptomatic patients or those with progressing stenosis, is essential to optimise outcomes. This article explores the nuances of AS diagnosis, treatment decisions, and the importance of patient involvement in the care pathway.

Does curcumin reduce inflammation and possibly lower raised LP (a)?

Research indicates that approximately 20% of the global population has elevated Lp(a), making it a prevalent, yet under-recognised, CVD risk factor. Despite its clinical significance, the management of elevated Lp(a) remains challenging. Standard lipid-lowering therapies, including statins, have little to no effect on Lp(a) and may even slightly increase its levels. However, emerging therapies such as PCSK9 inhibitors and innovative supplements like curcumin are shedding light on potential strategies to mitigate this risk.

Why do patients in atrial fibrillation get breathless?

In atrial fibrillation or AFib, the atrial tissue quivers at approximately 600 cycles per minute, which means that it has no useful pumping function. The left atrium therefore, in patients with atrial fibrillation, merely acts as a passive conduit between the lungs and the left ventricle. It no longer serves to prime the left ventricle, and as a result, less blood enters the heart during diastole, less 'priming' occurs so cardiac output may fall. If ever you have experienced a car's turbo charger going 'on the blink' you will know that the car still GOES, but not very well, since it too suffers loss of output.  The left atrial pressure in many such cases will increase, causing oedema or fluid in the alveolar space, reducing gas exchange and contributing to the symptom of breathlessness.