Providing independent clinical excellence since 2005
Traditional health improvement plans assume everyone responds the same way. Real life tells us otherwise. N-of-1 explains how to use a personalised, precision-medicine approach to reduce visceral fat, stabilise metabolism and rebuild long-term health. Through weekly reflections, practical tools and small self-experiments, the book guides you to uncover what truly works for you — not for the average patient, but for your own unique physiology.
In 2025, with access to low-dose CT angiography, FAI analysis, and a deeper understanding of plaque biology, it is increasingly difficult to justify CAC scoring in younger individuals.
VAT is the principal metabolic culprit in cardiovascular risk. BMI—while simple—fails to capture fat distribution, muscle mass, or ageing effects. Waist-based anthropometrics, particularly waist circumference and waist-to-height ratio, more closely reflect VAT and strongly predict cardiovascular outcomes.For cardiologists, this explains why a tape measure around the waist is more valuable than a BMI calculation. Where precise measurement is required—such as in high-risk patients commencing GLP-1 therapy—DEXA and low-dose CT provide direct VAT quantification.In both prevention and clinical practice, tracking waist measurements makes far more sense than relying on BMI.
Cardiology groups, including ours, are increasingly partnering with diabetes and weight management specialists to set up GLP-1 mimetic clinics. These clinics oversee VAT loss and improve glycaemic control for patients with diverse cardiac conditions. The goal is not only to help these patients manage their symptoms but also to provide a holistic approach to cardiovascular and metabolic health, with an emphasis on reducing the burden of visceral fat. Specialist clinics offer patients the chance to access personalised care that targets both fat loss and better glucose regulation, reducing the need for medications and potentially improving overall quality of life. In this blog and associated podcast and YouTube explainer, we set out some of the fundamental principles we care about.
Most men over 30 will recognise the slow but steady expansion of the waistline. Whether you call it a spare tyre, a dad bod, or just a bit of extra padding, not all belly fat is created equal — and not all of it is harmless.Some types of abdominal fat are mostly cosmetic. Others are dangerous, inflammatory, and metabolically active — the kind of fat that silently drives heart attacks, strokes, dementia, and even advanced cancers.Let’s break down the three main culprits behind the male belly — and what you can do about them.