Coronary heart disease Archives | Surrey Cardiovascular Clinic

The SCVC Blog

Cardiovascular care news and articles from our expert team

How a daily junior aspirin can save millions of lives

Aspirin, or acetylsalicylic acid, is one of the oldest and most widely used medications in the world. Well known for its analgesic effects, it was later discovered to be effective in much smaller doses in preventing platelet aggregation that had a pivotal role in arterial thrombosis. Its role in inhibiting platelet activity has made it a cornerstone in the prevention and treatment of arterial thrombosis. In this article, we will explore the fascinating role of platelets in acute coronary thrombosis, the mechanisms by which aspirin exerts its protective effects, and the clinical considerations for its use.

So what does determine your LDL (‘bad’) Cholesterol?

Statins are a mind boggling biological 'ruse'. When this medication is taken orally, it causes liver cells to become deficient in essential cholesterol, so they respond by increasing the number of cell surface LDL receptors, thereby enhancing their capacity to extract LDL particles from the blood, significantly lowering circulating LDL levels. Statins remain the most effective and well-known way that doctors can lower LDL levels to prevent or treat coronary heart disease.

Imagine if you could predict a heart attack

The idea of predicting a heart attack may have once seemed like science fiction, but it is rapidly becoming a reality. With the advent of advanced imaging techniques and artificial intelligence, we are now able to detect the early signs of coronary heart disease and intervene before a heart attack occurs. This represents a major shift in the way we approach cardiovascular care, moving from a reactive model to a proactive one.

Is coronary artery calcification good or bad?

Recognition that significant coronary artery disease exists without calcification led to the wider user of contrast-enhanced CT scans to detect both calcified and noncalcified plaques. Even more advanced scans identify not only the non calcified plaques, but also areas of inflammation (using data processing to measure FAI), that a non-contrast CT (such as a CAC scan) would otherwise miss. Sequential CAC to follow up disease progression quickly established that an increase in CAC with age was inevitable in most patients and not linked to clinical course, so is not widely practiced.

Is an elevated Homocysteine causing your heart disease?

Numerous epidemiological studies have supported the hypothesis that high homocysteine levels are a risk factor for cardiovascular diseases. For example, the Framingham Heart Study demonstrated that individuals with homocysteine levels in the top fifth percentile had a nearly doubled risk of developing coronary artery disease compared to those with levels in the bottom 80 percent.